If it's a pretty big red... yes. I even wrote a similar post a while back. Leaving a bottle uncorked overnight is equivilent to leaving a glass of wine on the table for hours because of the exposure to a greater surface area in the glass. I'm finding more and more that most big reds need lots of time to breathe. Your instincts are probably pretty good.
A few weeks ago I opened a bottle of Malbec (a type of grape mostly popular in Argentina but used mainly as a blending grape in other countries) with my friend and wine maker who'd stopped over. We poured our glasses full and were like, hmmm, it's pretty good. We got to talking, then my mom called and said she was stopping by. Friend left, hours passed as I straightened up, mom came over, talked with her. She left. I got a few phonecalls. It was hours and hours later that I got back to it. I picked up the glass and was shocked by how awesome the wine was. It really drove home how much breathing a wine might really need. Leaving a bottle open overnight or for a day is not as great and exchange of molecules as a glass, if you see what I mean. So sure, as long as it's not too warm out and the bottle isn't too empty.