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Friday, August 30, 2013 10:34:25 AM
" We have found that MANF can protect and stimulate proliferation of b -cells in a mouse model of type 1 diabetes. In addition, we generated mice which lack MANF protein, resulting in development of T1D. Since MANF has direct effects of mouse b -cells and is expressed and regulated in human b - cells we hope that MANF has therapeutic potential for the treatment of T1D, where b -cell protecting and regenerating therapies are not available" says Professor Mart Saarma.
Text: Maria Lindahl
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