Visionaries who are founders of companies are often the perfect "idea man", brilliant and able to create the spark that catalyses the startup of a revolutionary product, but as time goes on many of them do not fit the mold of a product manager, since their creativity and enthusiasm can get in the way of the boring details of just running the company with a dry focus on execution, coordination of plans and projections, and handling of commercial business deals including product launch. At later stages of company growth, the ideal "idea man" is better off passing the torch to an experienced industry CEO when the time comes.
The lifecycle of a revolutionary developmental stage biotech is very susceptible to this phenomenon. A brilliant researcher can be the brains or inspiration behind the company, but sooner or later the company needs someone with expert experience with the real world to coordinate and execute on product launches.