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Re: hugh_jackoman post# 6581

Thursday, 08/22/2013 8:08:00 AM

Thursday, August 22, 2013 8:08:00 AM

Post# of 40501
Conclusion by Novartis:

Conclusions

Self-amplifying RNA vaccines hold promise as next generation nucleic acid vaccines, but may
require delivery technologies to enhance potency. Electroporation in situ has been demonstrated to be very efficient for increasing delivery and effectiveness of plasmid DNA vaccines. We show here that electroporation can also be used to markedly enhance the delivery and potency of RNA-based vaccines



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