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Re: BonelessCat post# 38404

Thursday, 08/15/2013 12:11:34 AM

Thursday, August 15, 2013 12:11:34 AM

Post# of 403103
BK - Is this what you are referring to? It refers to DF but really the relationship between Harvard and DF is such that they often are mentioned in the same breath. This is from Karin CA'a interview with Leo in March:

: Cellceutix has identified p21 as a biomarker as a barometer of p53 expression for the clinical trial. Seeing activity of p53 without toxic side effects could be the Holy Grail for developing a new cancer treatment. When do you expect results from testing of the p21 biomarker? What are your expectations?

A: We are anticipating the tests to be run in mid-March and the results to follow shortly thereafter. Honestly, we were extremely pleased that the Dana-Farber laboratory is running these tests so early in the trial. It is a "no lose" situation for us as we did not anticipate biomarker testing, nor did we expect to see any activity, at this early stage and low dosing levels. If p21 activity is shown, we think that we have hit a home run, but if activity is not demonstrated, we will not be the least bit disappointed at this juncture in the trial. We will simply then wait for the testing at higher doses as we expected, where we are very optimistic that we will see p21 expression at that time.

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