Avid Bioservices Inc (CDMO)

[entdoc]

cjgaddy,a prince. all that about betabodies...related PPHM patents, and BB pharmacology. Lesson learned: B2GP1 is a compound that must be reckoned with. Is it correct that fully humanized Bavi does not require B2GP1-cofactor to bind to -PS? If true, fully human Bavi packing a cytotoxic payload makes as much sense as betabodies. I can foresee more potential areas for complications/side-effects with Beta-bodies, and, again, I do not see a wide enough cancer kill-zone. Naked Bavi, okay. Throw it in. Beta-bodies, why not. But for large tumors, especially with metastases, we need Cytoxin-bearing missiles like Cotara and humanized Bavi.