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Saturday, June 29, 2013 4:17:13 PM
At this point PPHM does not suffer any negative connotations in the medical community. PPHM has, in the years I have been a stockholder, not stepped over (or even close to) the line of being deceptive/unethical in their reports to the scientific community.
That's how everyone gets comfortable with each other in the broad pipeline of investigative clinical studies. Studies on advanced disease, such as advanced lung cancer, are done to give a realistic estimate of safety. Any efficacy is a bonus. If an agent shows ANY effect on advanced disease, it might well have a profound effect on early disease. And now we know Bavi can probably be used safely in earlier disease. Can the scientific community get behind a Bavi- based therapeutic platform? I think so. The stability of the platform is hinged on safety and sensibility. It appears we might be okay on both. Bavi-based product continues to make sense...even after being starved and parched in the clinic outback for years (AKA India, Russia, China trials). IMO we know pretty much what "naked Bavi" can do. It makes sense to use it early and often. Next clinical trials should be during and after irradiation. Armed Bavi. Imaging Bavi. Bavi with chronic disease. Use it for smaller, earlier, and less lethal disease. The fact that most informed observers are still aboard speaks for their continued willingness to let Bavi show its stuff.
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