Why would they not take this drug combination to phase III? First of all because the 14+ months result, while good, is not that much better than SOC. BUT MORE IMPORTANTLY BECAUSE THEY HAVE BETTER COMBINATIONS FOR FIRST LINE NSCLC! I'll bet the Bavi/pemetrexed trial is far enough along to show much better results in first line NSCLC! And they are also clearly stating that "...new immunotherapy combination studies are being planned."
Meanwhile they are focussing on the phase III second line NSCLC trial. King said, " The recent agreement with the FDA on the Phase III trial design, along with the successful fundraising efforts have positioned us well for advancing the program into Phase III development, and have strengthened our position to develop the compound including ongoing PARTNERING DISCUSSIONS."
Later on they speak of PS targeting antibodies "...SUCH AS BAVITUXIMAB..." signalling that some of the second generation embodiments will start moving forward. This is all good news for those like me who believe that it is a combination of immunotherapeutics will be the road to tolerable treatments of cancer that will lead to its CURE! The human immune system is the most powerful cancer killer in the world...current cancer treatments which kill the immune system are archaic and barbaric.
Now they have FDA approval for the phase III second line NSCLC trial and $40 million to proceed. Steadily increasing AVID revenue and IMHO a partnership close at hand. And they own the world wide PS franchise which offers a safe and powerful target to attack all cancers and all enveloped viruses. I think we will learn more soon.
