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Saturday, June 22, 2013 6:35:25 PM
I would challenge anyone to theorize how Bavituxmab could incounter an incipient tumor mass and trigger an effect of immunity, knowing in the least these two obstacles.
1) CTL (cytotoxic T lymphocytes) responses almost always begin in lymph nodes
2) The relative lack of high avidity T cell receptors are a major reason why immune responses towards tumor antigens are often non-protective.
This is just the tip of the iceberg when considering bavituxmab as a vaccine. Remember, in order for there to be immunity the most basic thing must happen, and that is, "memory anti-tumor CTL response". I contemplate this everyday, because I know there's an answer in bavituxmab somewhere.
All the best,
John
Disclaimer: Every post, and all my views are only speculative. Do not invest money or any other resources based on these post or opinions. Best of luck and do your own due diligence!
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