Avid Bioservices Inc (CDMO)

[The Other Guy]

As a non-science guy, when I read that each bavi molecule needs to grab two B2GPIs in order to attach to PS my first instinct was to consider the 2nd line NSCLC trial. Of the three arms in the study, the one not tampered with was the 3mg arm. Was the 3mg dose too much bavi therefore overall results could have been even greater than what they were had the dose size been more proper to the available B2GPI? What I mean by this is could 3 Mg be too much bavi so only one B2GPI would attach to many bavi molecules and not have the same impact as say, a lessor amount that could optimise that number of B2GPI attached to bavi? Possibly the optimum level is closer to 1 Mg? And, therefore, knowingly or not, the tampered arm was the one with greatest potential?