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Re: derrickcan post# 8244

Friday, 06/21/2013 9:03:42 AM

Friday, June 21, 2013 9:03:42 AM

Post# of 20775
There are a number of possible Pharma's including Lonza as noted below. We all can speculate but I believe the IP value for these large pharma's in their portfolios has significant value as many have expiring rights to drugs and are looking for new opportunities. The question is can Maza and Evli get a good deal done to "maximize shareholder value" as he said in PR. I sure do hope so!

Here is paragraph from earlier PR this year on Lonza:

Our lead program, CONJUMAB-A, offers an important advantage to the Aß antibodies currently in clinical development for both AD and AMD by several large pharmaceutical companies. This is because those antibodies (e.g. solanezumab, bapineuzumab, gantenerumab, crenzeumab, RN6G and GSK33766A) are designed for a single purpose, namely to clear Aß, while none act on the important secondary neurotoxic mechanisms, such as oxidative stress that causes most of the damage from Aß. By contrast, CONJUMAB-A is empowered with a potent antioxidant. An important step in establishing proof-of-principle was the initial data generated through our collaboration with iNovacia to evaluate compounds synthesized by Lonza for Intellect. The data demonstrated the conjugation of the antioxidant molecule to an amino acid does not reduce its antioxidant activity. Pending adequate financial resources, these studies, which are almost complete, will allow us to select a drug candidate to take into development, providing the trigger for us to move forward with LONZA into an expanded manufacturing project, bringing us closer to the submission of an Investigational New Drug application."
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