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Thursday, 06/20/2013 9:17:42 AM

Thursday, June 20, 2013 9:17:42 AM

Post# of 346050
Its all about the IP:

Strong intellectual property is a valuable asset for Peregrine and we will continue to seek robust patent protection for key areas of our research and development efforts. Our extensive patent portfolio covers a number of technologies, including our drug product candidates and preclinical platforms.

Peregrine holds or has an exclusive license to over 200 issued patents and published patent applications worldwide. These include patents directed to imaging and treating cancer using antibodies and immunoconjugates that target phosphatidylserine (PS) and phosphatidylethanolamine (PE) exposed on tumor blood vessels. Our lead PS targeting antibody bavituximab is protected by several composition and method patents, including those directly supporting our clinical programs of treating cancer and viral infections using bavituximab in combination therapies. Peregrine also holds composition and method patents for our novel cancer therapy Cotara®.

In addition, our intellectual property covers a wide range of antibody conjugates, families of anti-VEGF antibodies and PE-targeting peptide conjugates and their use in a range of therapeutic methods, such as treating solid tumors and viral infections.

http://www.peregrineinc.com/about-us/intellectual-property-.html
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I think partnering talks would ultimately come down to this conclusion: IF Bavi is what makes combination therapies work "better" ... work more "effectively" .. .work "safely"... and ultimately show that it works well,

Would not the "bavituximab" be the driving force behind a BP's motive to run a set of trials that would make it very difficult for all others to compare to?

There is talk of rumbles of drugs and active ingrediant and how the costs are split.... In my book, if Bavituximab is causing the curves to straighten out, if Bavituximab is allowing those to live longer, if Bavituximab as a safety profile like no other.

The answer is obvious to me... its not IF they will partner, its WHEN and with WHO.

Hopefully, this will be answered very shortly, since BP's realize that time to market is critical-- and Phase III ready to go now.

GLTA!

"Bavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that is the cornerstone of a broad clinical
pipeline."
-- Big Pharmas nightmare... unless they are fortunate enough to have The Bavi Edge!

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