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Re: jaybe post# 162579

Saturday, 06/15/2013 10:07:46 PM

Saturday, June 15, 2013 10:07:46 PM

Post# of 252358

Why is LDK378 considered 2nd generation ALK?



Because it has dramatically better potency against ALK than does criz, and it is effective in some patients that failed criz. Its potency is in the same general ballpark as '113.

You really can't compare across trials like you are doing - the patient populations can be very different.

Peter

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