Pacific Biosciences of California Inc (PACB)

[Paulieme]

Long read,but very good info! For example, the fraction of the GC-poor
P. falciparum genome that had relative coverage = 0.25 (i.e. four-fold undercovered or
worse) ranged from 0.33% in Pacific Biosciences data (PACB BEST) to 3.7% in Illumina data to
22% in Ion Torrent data (worst). In the GC-rich R. sphaeroides genome, the four-fold
undercoverage fractions were 0.0071% for Pacific Biosciences (PACB BEST), 0.39% for Illumina,and 36% for Ion Torrent (worst). The better performance of Pacific Biosciences is probably
attributable to the lack of any amplification in their process. ( Characterizing and measuring bias in sequence data
Genome Biology 2013, Publication date 29 May 2013
Article URL http://genomebiology.com/2013/14/5/R51 (cf. [20, 21]). Characterizing and measuring bias in sequence data
Genome Biology 2013, 14:R51 doi:10.1186/gb-2013-14-5-r51
Michael G Ross ([e-mail])
Carsten Russ ([e-mail])
Maura Costello ([e-mail])
Andrew Hollinger ([e-mail])
Niall J Lennon ([e-mail])
Ryan Hegarty ([e-mail])
Chad Nusbaum ([e-mail])
David B Jaffe ([e-mail])
ISSN 1465-6906
Article type Research
Submission date 11 December 2012
Acceptance date 15 May 2013
Publication date 29 May 2013
Article URL http://genomebiology.com/2013/14/5/R51 For the whole read click on LINK and then click on provisional PDF