Biotech Values

[ariadndndough]

jq and biomaven great discussion on aria. curious if you guys have any more thoughts on 113 in EGFR.

jq you mentioned
113 EGFR T790M does have hint of efficacy. Once test of presence of T790M mutation before entry criteria is used, result could surprise because none of 5 patients with documented T790M during most recent EGFR TKI treatments had progressed (2 SD, 3 NS). As of how it would compare to CO1686, it is impossible to say at this point. I do think surprise could come here rather than ALK because of competitive landscape

surprise? can you elaborate more?

thanks agian learning all the time

dough