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Re: Fire Fox post# 126490

Thursday, 06/06/2013 6:37:03 PM

Thursday, June 06, 2013 6:37:03 PM

Post# of 345950
Fire Fox,
I believe the reason the squamous patients were excluded in both the Avastin and Bavi first-line trials
was due to a concern for adverse events. In the Bavi case I don't think there is any reason to think
it would not work as well in the squamous cell type. If I remember correctly, this was a question put
to Steve King at the annual shareholders meeting and he said that it would be something worth doing.

"By all means let's be open-minded, but not so open-minded that our brains drop out." - Richard Dawkins

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