Imaging Diagnostic Systems (fka IMDS)

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~IMDS 3D Laser Breast Imaging System Demonstrates Significant.Results http://www.marketwatch.com/story/ctlmr-3d-laser-breast-imaging-system-demonstrates-significant-results-when-imaging-dense-breasts-2012-12-11

http://www.imds.com/ctlm/CTLM-Patents.php

CTLM(R), 3D Laser Breast Imaging System, Demonstrates Significant Results When Imaging Dense Breasts

FORT LAUDERDALE, Fla., Dec 11, 2012 (GlobeNewswire via COMTEX) -- Imaging Diagnostic Systems,
Inc. , a pioneer in laser breast imaging, announced today that Clinical Imaging, a leading US based
radiologist peer review journal, has reviewed and accepted a paper that evaluates the results of
CTLM(R) and mammography when imaging dense breasts.

The recent paper accepted by Clinical Imaging focuses on imaging women with heterogeneously and
extremely dense breast tissue using both mammography and CTLM(R). CTLM(R) is an innovative 3D
laser breast imaging system that utilizes Diffuse Optical Tomography or "DOT" technology. The
study demonstrated that the addition of a CTLM(R) scan to a mammogram improved sensitivity rates
of detecting breast abnormalities considerably. The sensitivity rates ranged from 34.4% for
mammography alone to 81.57% when CTLM(R) was added. Equating to over double the sensitivity to
detect abnormalities when imaging extremely dense breasts (ACR BIRADS 4 breast composition
classification). To access the free abstract and the complete clinical paper for purchase, please go to
http://www.clinicalimaging.org and search under the heading for either "CTLM" or "CTLM as an adjunct to
mammography in the diagnosis of patients with dense breast". Globally, 40-50% of the female
population have mammographically dense breasts and these recent results present the potential of
CTLM(R) to assist the imaging needs of women with any breast density.

Clinical Imaging provides widespread coverage of innovative technology, new applications, and
important issues concerning all diagnostic imaging techniques. The journal investigates the relative
merits of established and developing diagnostic imaging technology, with regard to cost
effectiveness, safety, and propriety where specific disorders and physiological systems are
concerned. Clinical Imaging is a radiologist peer reviewed publication. From ultrasound to MRI,
Clinical Imaging provides crucial information for radiologists, radiology residents, and radiologic
technologists.

The paper's author, Dr. Jin Qi remarks, "Our data indicated that the imaging of CTLM(R) was least
affected by tissue density in breasts and provides information about angiogenesis in breast lesions,
especially in malignant lesions, when used as an adjunct to mammography in heterogeneously
dense breasts and extremely dense breasts, sensitivity increased significantly." Dr. Qi concluded,
"this is a feature that could have a positive impact on women's imaging across the globe." Dr. Qi is
deeply involved with breast cancer in China and works in the following departments; Radiology
Department at Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast
Cancer Prevention and Therapy of the Ministry of Education, and Key Laboratory of Cancer
Prevention and Therapy.

CEO of Imaging Diagnostic Systems, Inc., Linda Grable states, "IDSI is very excited and honored to
have a CTLM(R) paper accepted by a leading, well respected American diagnostic imaging
publication. The results display the capability of CTLM(R) to be less impeded by dense breast tissue
than mammography and will eventually provide radiologists with a complimentary non radiation
based imaging tool; especially when dealing with dense breast tissue. And the additional patient
benefits consisting of no radiation, no breast compression, and no injected contrast agents will
hopefully aide with women's imaging needs globally".

Imaging Diagnostic Systems, Inc. is the developer of the CTLM(R) system; a revolutionary optical
breast imaging device. Optical mammography is a diffuse optical tomography (DOT) technique that
aims at detecting breast cancer. The CTLM(R) system utilizes patented continuous wave laser
technology and computed algorithms to create 3D images of the breast. The procedure is non-
invasive, painless, and does not expose the patient to ionizing radiation or painful breast
compression. The CTLM(R) system has received certification and licenses to sell internationally
through the following approvals; European CE marking, Health Canada, China SFDA, UL, ISO
13485:2003, FDA export certification. Marketing clearances pending are Mexico COFEPRIS and
Russian GOST-R.

For more information, visit our website: http://www.imds.com