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Saturday, 05/04/2013 11:22:34 AM

Saturday, May 04, 2013 11:22:34 AM

Post# of 80490
Maybe this explains meeting with NVS...

http://www.ncbi.nlm.nih.gov/pubmed/23539538

Midostaurin has been in the lab for over 10 years, still not approved for an indication. Appears to overlap with several Pona targets, FLT-3, c-KIT, VEGFR-2, PDGFR . Most current trials are combo studies with chemo in AML.

Latest trial results from ASH 2012 leave something to be desired:
https://ash.confex.com/ash/2012/webprogram/Paper48129.html

I think we will see many more Pona combos as labs around the world understand Pona just makes their drugs better. I sense a nice revenue stream flowing with little to no outlay.

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