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Re: genisi post# 116681

Saturday, 04/27/2013 12:58:32 AM

Saturday, April 27, 2013 12:58:32 AM

Post# of 252233
DYAX

In the EU, Shire's Firazyr label was recently amended to include self administration as well, so it's the first and only SubQ self administered agent for acute HAE, an advantage that is hard to compete with. If approved with a similar label by the FDA, I expect it to gain a big share in the acute market. This of course will hurt Dyax's Kalbitor and CSL Behring's Berinert but not VPHM’s Cinryze.

What do you make of DYAX's DX-2930, which is set to enter the clinic middle of this year: http://www.dyax.com/angioedema-portfolio/research-development.html ? For more detail, see: http://investor.dyax.com/releasedetail.cfm?ReleaseID=742676 . It's basically a self-administered subQ, long-acting, prophylactic treatment for HAE. Do you see this as a drug that, if successful, could turn DYAX's HAE fortunes around?

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