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Saturday, 12/03/2005 1:11:43 PM

Saturday, December 03, 2005 1:11:43 PM

Post# of 82595
Working Hand in Hand ......

DNAPrint genomics and Moffitt Cancer Center .....

Moffitt will contribute gene expression and proteomics data resources currently in development and DNAPrint will contribute its ADMIXMAP platform and SNP analysis for mapping the genetic determinants of variable drug response by harnessing the power of human population genetic structure.

Over all of the program areas, the collaboration will combine Moffitt oncologists, research scientists, mathematicians and software engineers with DNAPrint computer scientists, molecular biologists and population geneticists, and draw upon DNAPrint’s pharmaceutical, clinical and regulatory expertise. Moffitt will contribute gene expression and proteomics data resources currently in development and DNAPrint will contribute its ADMIXMAP platform and SNP analysis for mapping the genetic determinants of variable drug response by harnessing the power of human population genetic structure. ‘We have identified several clinical projects at the Moffitt that are of keen commercial and social interest,’ said Dr. Hector J. Gomez, MD, PhD, Chairman of the BOD and Chief Medical Officer of DNAPrint genomics, Inc. ‘Each of these programs offers us the opportunity to advance cancer treatment in a significant way,’ he said. Recent (November 2003) FDA guidance regarding pharmacogenomics technologies promulgate that if markers are validated using well understood markers in legitimate clinical environments, genetic tests derived from those markers should be included in new drug applications.


Moffitt sees thousands of cancer patients each year, and ranks with M.D. Anderson (Univ. Texas), Johns Hopkins (Baltimore, MD) and Fred Hutchinson (Seattle, WA) as among the nation’s busiest and most prestigious cancer research centers. The center has established a domestic and international network of collaborating physicians to build patient registries and implement cutting-edge methods for reducing, treating or preventing the onset of cancer diseases.


“Moffitt scientists and physicians were impressed with DNAPrint’s ADMIXMAP approach for using a populations’ structure as a fuel for mapping drug response gene variants. We recognized its profound potential for contributing to the enhancement of cancer treatment”, said Moffitt’s Dr. Timothy Yeatman.

THIS STARTED IN MARCH 2004 --- GEO