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Biotech Stocks Outperform the S&P 500
A Brief History of Biotechnology
By Brian Hicks
Monday, April 8th, 2013

"We have the means right now to live long enough to live forever. Existing knowledge can be aggressively applied to dramatically slow down aging processes so we can still be in vital health when the more radical life extending therapies from biotechnology and nanotechnology become available."
— Ray Kurzweil

The 19th century French chemist Louis Pasteur is widely regarded as the father of the modern-day biotechnology industry.

If you remember your grade school lesson, Pasteur was a microbiologist worshiped for his breakthroughs in the causes and preventions of diseases.

Pasteur's discoveries reduced mortality from puerperal fever, and he created the first vaccines for rabies and anthrax. But perhaps he's best known for inventing a method to treat milk and wine in order to prevent it from causing sickness, a process called pasteurization.

It may surprise you to learn Pasteur wasn't the first to use biotechnology. In fact, humans have been experimenting with "biotech" processes for thousands of years.

Before I go any further, here's a quick definition: Biotechnology is the use of living systems and organisms to develop or make useful products.

Yeast is probably the best-know unicellular organism in this regard. And of course, you know it's used to make bread and beer. Well, that's biotechnology.

Sounds rather scientific and simple at the same time, doesn't it?

That's because it is...

Nearly 10,000 years ago, humans were producing wine, beer, and bread by using fermentation, a natural process in which the biological activity of one-celled organisms plays a critical role.

It wasn't until the 20th century that the life-changing impact of biotechnology was fully realized, marked by the discovery of antibiotics through biotechnology...

Alexander Fleming discovered the mold Penicillium in 1928. His work led to the purification of the antibiotic penicillin by Howard Florey, Ernst Boris Chain, and Norman Heatley.

In 1940 penicillin became available for medicinal use to treat bacterial infections in humans, and for the next 40 to 50 years, penicillin was the drug of choice to treat a whole host of infections.

The next big milestone for biotechnology came in September 7, 1984, when Amgen went public. On that day, the biotechnology industry changed forever as it ushered in a massive inflow of capital investment for R&D to target the world's deadliest diseases.

Amgen has now returned investors who purchased its stock on that day over 100,000%!

And ever since, investors have tried to find the next Amgen. Because no other sector in the market offers the breathtaking returns biotechnology does.

Think about it like this: What's the cure for cancer worth? Or heart disease, diabetes, obesity?

It goes further than that...

As you read this, biotechs all across America are researching ways to make you live longer with a superior quality of life. They're growing limbs and organs in labs. And they're researching drugs to eradicate some of the most terrifying diseases known to man, like Alzheimer's.

Each of these drugs — if successful — could be worth tens of billions of dollars.

That's the promise of biotechnology.

Etc.

http://www.wealthdaily.com/articles/biotech-stocks-outperform-the-sp-500/4148



The Nobel Prize in Physiology or Medicine 1945
Sir Alexander Fleming, Ernst B. Chain, Sir Howard Florey

Biography

Ernst Boris Chain was born on June 19, 1906, in Berlin, his father, Dr. Michael Chain, being a chemist and industrialist. He was educated at the Luisengymnasium, Berlin, where he soon became interested in chemistry, stimulated by visits to his father's laboratory and factory. He next attended the Friedrich-Wilhelm University, Berlin, where he graduated in chemistry in 1930. He was from an early age interested in biochemistry and after graduation he worked for three years at the Charité Hospital, Berlin, on enzyme research. In 1933, after the access to power of the Nazi regime in Germany, he emigrated to England. Here, his first two years were spent working on phospholipids at the School of Biochemistry, Cambridge, under the direction of Sir Frederick Gowland Hopkins, for whose personality and scientific ability he came to have a great admiration.

In 1935 he was invited to Oxford University where he worked in the Sir William Dunn School of Pathology, becoming, in 1936, demonstrator and lecturer in chemical pathology. In 1948 he was appointed Scientific Director of the International Research Centre for Chemical Microbiology at the Istituto Superiore di Sanità, Rome. He became Professor of Biochemistry at Imperial College, University of London, in 1961, which position he still holds.

His research has covered a wide range of topics in addition to those already detailed. From 1935 to 1939 he worked on snake venoms, tumour metabolism, the mechanism of lysozyme action and the invention and development of methods for biochemical microanalysis. In 1939 he began, with H. W. (now Sir Howard) Florey, a systematic study of antibacterial substances produced by micro-organisms. This led to his best known work, the reinvestigation of penicillin, which had been described by Sir Alexander Fleming nine years earlier, and to the discovery of its chemotherapeutic action. Later he worked on the isolation and elucidation of the chemical structure of penicillin and other natural antibiotics. Since 1948 his research topics have included carbohydrate-amino acid relationship in nervous tissue, a study of the mode of action of insulin, fermentation technology, 6-aminopenicillanic acid and penicillinase-stable penicillins, lysergic acid production in submerged culture, and the isolation of new fungal metabolites.

Professor Chain is author or co-author of many scientific papers and contributor to important monographs on penicillin and antibiotics. He was in 1946 awarded the Silver Berzelius Medal of the Swedish Medical Society, the Pasteur Medal of the Institut Pasteur and of the Societé de Chimie Biologique, and a prize from the Harmsworth Memorial Fund. In 1954 he was awarded the Paul Ehrlich Centenary Prize; in 1957 the Gold Medal for Therapeutics of the Worshipful Society of Apothecaries of London; and in 1962 the Marotta Medal of the Società Chimica Italiana. He was elected a Fellow of the Royal Society in 1949. He holds honorary degrees of the Universities of Liège, Bordeaux, Turin, Paris, La Plata, Cordoba, Brasil, and Montevideo, and is a member or fellow of many learned societies in several countries: these include the Societé Philomatique, Paris; the New York Academy of Medicine; the Accademia dei Lincei and the Accademia dei XL, Rome; the Académie de Médicine, Académie des Sciences, Paris; the Real Academia de Ciencias, Madrid; the Weizmann Institute of Science, Rehovoth, Israel; the National Institute of Sciences, India; the Società Chimica Italiana; and the Finnish Biochemical Society.

He is a Commander of the Légion d'Honneur and Grande Ufficiale al Merito della Repubblica Italiana.

Professor Chain married Dr. Anne Beloff in 1948. They have two sons, Benjamin and Daniel, and one daughter, Judith. Music is one of his recreations.

From Nobel Lectures, Physiology or Medicine 1942-1962, Elsevier Publishing Company, Amsterdam, 1964

This autobiography/biography was written at the time of the award and first published in the book series Les Prix Nobel. It was later edited and republished in Nobel Lectures. To cite this document, always state the source as shown above.




Ernst B. Chain died on August 12, 1979.




http://www.nobelprize.org/nobel_prizes/medicine/laureates/1945/chain-bio.html

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