The most comprehensive guidelines come from NCCN...
Also referenced on page 3 of the RengenceRx piece.
See link for summary of NCCN guidelines, check out page 12, where Pona is recommended first for all mutuations. Ponatinib summary on pages 20-26. I like the summary slide, page 26, "[Ponatinib is]expected to significantly improve outcomes of CML and Ph+ ALL".
(By the way if you want to see what a dirty drug profile looks like check out Bosutinib on page 16.)
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