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Re: JJM760 post# 28788

Saturday, 04/06/2013 12:00:08 PM

Saturday, April 06, 2013 12:00:08 PM

Post# of 80490
Best in class for ALK will be demonstrated at ASCO. However, a teaser for this potential will be presented this Wednesday at AACR.

From abstract #5655..."Importantly, since AP26113 maintains potent activity against mutant forms of ALK and ROS1 at concentrations substantially below its human trough concentrations these data suggest that AP26113 may be able to prevent the emergence of drug-resistant mutants in NSCLC patients."



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