Friday, April 05, 2013 2:35:26 PM
Two weeks ago I was at a CNS drug development meeting where someone from NIH polled a few of us to shelved mechanisms that deserve another chance (NIH has some money they are putting into this concept). As I usually do, I mentioned Ampakines, and a few Big Pharma people nodded their heads. But none of them have painkiller-induced RD anywhere on their radar, and the diaspora of ex-Lilly people around the industry means that several companies have scientists who say--'we couldnt solve Ampakines, so they're not solvable'. RD is not an indication NIH is considering.
If someone can run a Phase II that gives convincing 'proof of principle' (an illusory term, the way it's used at present), they'll find a buyer, I believe. Probably a pain company. Why a pain company hasnt stepped up thus far is something we have all wondered about, it's a discredit to the industry.
Cortex's market cap must be in the $5 million range, and they'd probably need $10 million to put themselves in position. Lippa may have an idea--and resources--to get there, but it would be ugly. If instead, keeping in operation for the sake of dronabinol is the goal, and Pier's participation in the takeover leaves that open as a possibility, that would be a lot cheaper, but that would leave Ampakines on the shelf, perhaps forever.
NP
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