Biotech Values

[poorgradstudent]

ARIA:

I wonder if they should try dose titration similar to Jakafi

Agree with this. Given the efficacy, it's the best way to proceed. The IC50 values also support this type of management.

I don't mean to lessen the fact that the drug causes AEs. The review documents at the time made that clear. However, this report says pancreatitis is running at ~30% versus 6% on study. Without seeing what the exact data are, I do suspect there is a bit of sensationalism in the analyst note.