The daily share volume has gone to 1 million versus 300,000 a week ago.
I have started accumulating. In two pumps last Aug and Sept, it shot up to 53 cents when it had zero activities in FDA trials, just announcements on appointment of legal firm (a reputable one), trial experts (two of them are well known), a pharmacy to make the drug (a long established firm) and a Investor Relations firm (also long established).
There has been no news since then but it is a requirement of SEC that ESSI has to issue updates that are material to the share price if there are events.
I think an update can come anytime in the next few weeks.