jaybe have your read this entire article Ponatinib (AP24534), a multi-targeted pan-FGFR inhibitor with ... mct.aacrjournals.org/content/.../1535-7163.MCT-11-0450.full.pdf http://mct.aacrjournals.org/content/early/2012/01/10/1535-7163.MCT-11-0450.full.pdf