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Re: mantis post# 27493

Thursday, 03/21/2013 5:11:13 PM

Thursday, March 21, 2013 5:11:13 PM

Post# of 403756
If they cannot disclose any statistical information we will not be able to get a feel for how much tumor suppression is going on. For example we will not hear there has been 50% increase in p21 from baseline, this could be correlated to some degree of tumor suppression (certainly not by me). The larger the increase in p21 presumably correlates to how much p53 is being activated and how much tumor suppression is going on.

For me this makes this announcement somewhat safer if the answer is yes because we will only be able to speculate then. Interestingly, it sounds like Leo is planning to release statistical numbers on p21 at ASCO? If true we know that was not part of the abstract submitted back in February and opens the door to CTIX giving us updated information at ASCO?

As always IMO