Cashking, Onko Sure will never be successful as a screening tool for cancer. All you have to do is the math. Even at 95% specificity, there would be 50 false positives for each actual case of cancer discovered. That is why DR-70/Onko Sure never developed any market. Radient attempted to market it back in 2001 but it failed miserably due to false positives.
MacLellan held a conference call about Onko Sure back in June 2011 at the height of the India hype. I called in and asked a question about screening, gave him the stats right out of the government website and in response, he said, "You are correct about the false positives in a general screen. That is why we are pre-screening in India." As it turned out, half of the people pre-screening in India were selected as candidates for being given an Onko Sure test. No tests were ever administered but with 50% eliminated, the false positives would still be 25 for every actual cancer detected.
The test is just not going to be accepted in any way by the medical community.
IMO, the company data does not even support a 95% specificity because in that study, they eliminated from participation anyone with a heart condition, intestinal problems and several other conditions that would cause a high fibrin level.
Onko Sure is just not a useful test.
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