Avid Bioservices Inc (CDMO)

[entdoc]

King, on BAVI IMAGING: What is a "-PS index"? Any company wanting to develop a new anti-cancer drug may, in the future, be able to see on a screen in real time how effective their candidate drug is at attacking the cancer by monitoring how much -PS is created in and around the cancer. How? PS is expressed in dead and dying cells and in cancer cells. Labeled Bavi injected (or oral) collects at the cancer site where increased PS is being produced if the anticancer agent is effective in killing cancer cells. Something like the "PS index" will be established to determine the cancer lethality of a drug. This ability to see in real-time the action of anti-cancer drugs could potentially obviate the need for cancer drug clinical trials as we know them, and save a huge amount of money for drug development. Pretty amazing that Bavi may be used to monitor drug anti-cancer effectiveness even if, worst case scenario, it turns out to not be highly useful as an anit-cancer agent...etc.etc.