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Tuesday, February 19, 2013 12:30:06 PM
Could you please help me confirm an important point that appears to make Bavi results today even stronger. In you post #110144 your chart reports that in the Bavi 3mg arm 24.4% of the patients were ECOG PS 2. Where did you get that number? Was it based on all 40 patients as reported back in Sept.? Is it still a valid number today?
ECOG PS 2 patients are MUCH sicker than the PS 0 and 1 patients.
Everyone should review FTM's chart in post 110144 and notice that the 3 other trials reporting treatment arm MOS greater than 10 months (i.e. Herbst in 2010, Pallis in 2010 and Ramlau in 2012) had PS 2 populations of only 1%, 11.9% and 4.6% respectively.
BPs will surely notice that Bavi achieved MOS of 11.7 months in a patient population having twice as many very sick PS 2 patients.
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