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Re: keep_trying post# 112437

Monday, 02/18/2013 8:11:23 PM

Monday, February 18, 2013 8:11:23 PM

Post# of 345846
<< My call out is that the MOS can indeed get better by showing longer survival for censored patients that event than survival indicated by an interim result-- if censored patients event over time where there are more patients that event "to the right" of the interim MOS value than to the left >>


Correct. Furthermore one can argue that the 3mg Bavi patients that were censored last time they announced MOS in September were the ones that were still alive at that time and living longer than average for the arm, and if/when they event it is likely to push MOS to the right. Same goes for combo of 1mg Bavi plus placebo arms but to a lesser degree. IMO final MOS for 3mg Bavi will move to the right, and 1mg Bavi plus placebo combo may also move to the right but less than 3mg arm.
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