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Re: asmarterwookie post# 112440

Monday, 02/18/2013 2:20:00 PM

Monday, February 18, 2013 2:20:00 PM

Post# of 345976
I suspect that this is the same question as why can't we just drop the patients who got
the incorrect dosage from whatever arm they were in (placebo or 1 mg). I still feel the
reason this hasn't been mentioned by Peregrine is that there were too many patients who
got one incorrect dose, so the number of remaining patients would be too small. However,
I also still feel that one incorrect dose in many patients would have a very small effect on
the outcome of the control arm. There is another aspect to this too. It could be that
dropping patients could result in very unbalanced arms as far as patient characteristics go.
Hopefully when the data comes out this will be made clear.
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