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Re: Fire Fox post# 112051

Thursday, 02/14/2013 5:52:02 PM

Thursday, February 14, 2013 5:52:02 PM

Post# of 345970
FF, both the Abraxane study and the FOLFIRINOX study were done with only metastatic patients,
just as the Peregrine trial was done. FOLFIRINOX is a combination of 4 chemo drugs, and
Abraxane is albumin-bound paclitaxel. So the big difference was adding a monoclonal
antibody to gemcitabine, instead of more chemo drugs. I agree with your assessment that the
patients were dying faster than bavi could work. It will be interesting to see if
there was a subset that did better.
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