A quote from 'Tumor Models in Cancer Research

A quote from 'Tumor Models in Cancer Research (2nd edition)' edited by Beverly Teicher:

from page 7:

"...one can conclude that agents irrespective of their level of in vitro activity which have activity in less than 33% of [mouse] models tested had no "positive" phase 2 clinical trials. In contrasts, agents with activity in at least 33% of such models had an approximately 50% likelihood of positivity in phase 2 clinical trials."

Hmm, I wonder what the likelihood of positive phase 2 results is in an agent with activity in 100% of the mouse models tested.

A1


Tumor Models in Cancer Research