Avid Bioservices Inc (CDMO)

[seamoss58]

KT - wrt Avid MAb-ufacturing..

I ran my own numbers using what I could glean from internet
and the license agreement (Lonza).

This is my 'likely' scenario.
I could only get info on batch processes as continuous feed
is newer (and probably more trade secret protected).

However, I think the numbers are good (given the assumptions
I've made).

----------------------Likely
Cycle Time(days)----------20
Changeover(days)----------10
PM(days)------------------30

Run/yr------------------11.2



Yield(g/l)---------------3.5
dose(mg/kg)--------------1.2

doses/run--------------32407
*90kg patient
doses/yr--------------361883

medium($/l)-------------$120
other($/run)--------$100,000

cost/run($)-------$4,900,000

sales($/dose)---------$1,000

revenue($/run)---$32,407,407

profit($/run)----$27,507,407

profit($/yr)----$307,166,049

So you can see that the 1kL reactor isn't nearly big enough
to make a dent in the demand.

However, the profits could be large given a $1000 cost per
dose.

Food for thought/discussion.

cmos