Avid Bioservices Inc (CDMO)

[freethemice]

There is another way to look at the second-line NSCLC trial. It is just an exercise, but consider
the that the three arms are these
1) "effective" dose of 0.25 mg/kg
2) "effective" dose of 0.75 mg/kg
3) dose of 3 mg/kg

By "effective" what I mean is that the survival curves are what you would see if everyone got that dose
instead of the original dose. So the survival curve for original placebo arm is close to the curve that
would result if the patients got 0.25 mg/kg instead of just placebo. Then you have a progression of increasing
doses that increases survival in response. What the "effective" dose is would depend on what actually happened.
Just another way of looking at it.