Celsion Corporation (CLSN)

[sdtrond]

No you're confused.

I said, "My point is that TTP will be lower than PFS. Do you disagree on this?"

And you reply, "And, yes, I absolutely disagree by light years that TTP would be longer than PFS. How can it not?"

So which is it? I believe you simply wrote it wrong from context, since the rest of your post deals with your objection.

Here's my example. Let's say TTlP (time to local progression) is around 9 months. TTdP (distant) is 11 months. TTexP (ex-hep) is 14. And death is about 30 months.

So TTP might be 12 months but PFS (including all components) would be extended out becuase of the (admittedly few) events triggered by death without tumor progression.

As you say, GOOD GRIEF.

Your reasoning is flawed when you say,
"(1) There's lots of ways a PFS can happen.
(2) There's only one way a TTP can happen.
Therefore PFS is far more likely to happen -- and SOONER -- obviously!"

The sooner is incorrect.
Yes PFS EVENTS will occur more frequently than TTP events. But the actual VALUE of PFS can be pushed out by the non-TTP events.