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Re: Rawnoc post# 6761

Sunday, 01/06/2013 9:59:57 AM

Sunday, January 06, 2013 9:59:57 AM

Post# of 16750
"As to the rest of you post, it's just plain wrong. In one interview by one of the investigators he gave the example of a pancreatic cancer drug that only improves the mean progression by 3 weeks yet the FDA still approved it. 33% is not a "softball" since it stil represents months."

And pancreatic cancer is even worse than lung cancer. I'd be very willing to bet that approval you spoke of was for third line or further out? FDA always has to balance efficacy with safety, and we're talking a first line treatment here that could be in store for 12.5 to 35% of liver cancer patients worldwide. Better believe we'll be judged with a different eye.

Yeesh, every time I engage to try to counter some wild optimism I end up sounding bearish. Again, if its "way under 12 months" for placebo as you claim I'll be jumping up and down AND frst in line to congratulate you.

Any thoughts as to the enrollment issue?