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Friday, December 21, 2012 12:05:03 PM
been approved that don't have a good MOA described. Even now, 15 years after approval, papers
still appear about the MOA for rituximab (Rituxan), similarly for trastuzumab (Herceptin), and others.
The MOA for bavituximab has evolved from its original state to become more widely applied to treating
immunosuppression in the tumor microenvironment. I am sure there are more things to learn about
the MOA and how the anti-PS approach can be used to treat cancer. As we learn more new ideas about
treatment combinations with bavi will emerge.
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