Not entirely true. Sprycel doesn't have a black box warning. Tasigna does, but it is different than that of Iclusig's. However, I think the black box and safety findings with Iclusig are more problematic than those of Sprycel or Tasigna because there is significantly less follow-up and experience with Iclusig, and long-term data is a major factor in CML.
None of the people that I've spoken to are remotely worried.
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