Avid Bioservices Inc (CDMO)

[biopharm]

I think that extra production facility may come in handy to max the production of Bavi if Avid is unable to meet the full demand .... once the following side effect risks are considered vs Bavi's

Side Effects of Avastin below from: http://www.avastin.com/patient/lung/side-effects/index.html


The most serious side effects (not common, but sometimes fatal): (from the use of Avastin)

• Gastrointestinal (GI) perforation. A hole that develops in your stomach or intestine. Symptoms include pain in the abdomen, nausea, vomiting, constipation, or fever
• Wounds that don’t heal. A cut made during surgery can be slow to heal or may not fully heal. Avastin should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed
• Serious bleeding. This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; and vaginal bleeding. If you recently coughed up blood or had serious bleeding, do not take Avastin
Other possible serious side effects:
• Abnormal passage in the body. This forms from one part of the body to another and can sometimes be fatal
• Stroke or heart problems. These include blood clots, mini-stroke, heart attack, and chest pain. These can sometimes be fatal
• Severe high blood pressure. Blood pressure that severely spikes or shows signs of affecting the brain. Blood pressure should be monitored every 2 to 3 weeks while on Avastin and after stopping treatment
• Nervous system and vision problems. Symptoms include high blood pressure, headache, seizure, sluggishness, confusion, and blindness
• Kidney problems. These may be caused by too much protein in the urine and can sometimes be fatal
• Infusion reactions. These may include difficulty breathing, chest pain, and excessive sweating. Your doctor or nurse will monitor you for signs of infusion reactions
• Fertility issues for women. Avastin could cause a woman’s ovaries to stop working and may impair her ability to have children