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Post# of 252676
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Re: mcbio post# 153635

Thursday, 12/06/2012 7:14:02 PM

Thursday, December 06, 2012 7:14:02 PM

Post# of 252676
CDKs / Seliciclib:

Not much thought on this drug, but let me point out a neat feature of seliciclib that shows why i was skeptical of targeting CDKs:

- as you note, CYCC says it hits CDK2, 7 and 9

- Cayman says it hits CDK2, 5, 7 and 1

- Enzo says it hits CDK1, 2 and 5


I guess the consensus is that it hits CDK2, with a dash of CDK1, 5, 7 and 9

smile
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