RespireRx Pharmaceuticals Inc (RSPI)

[haysaw]

Nice post. Well, in the end (of the day or otherwise), I'd say we are all pretty fucked up. The difference, I think, is determined by how much your fuck up screws up others (and how many). I'd surmise Stoll, Varney,and NeuroInvestment did a pretty good job making a difference (at fucking up others, that is). Having an agenda is a curse, which unfortunately many of us bear in some shapes or forms. The agenda took hold of these people like an addiction. I realized they were BS a long time ago, but, stupidly, didn't sell. I don't blame them for my loss, I blame them for Cor's loss. Since loyalty is important to me, I would probably go through this again. Many times it pays off: this time it didn't. I have no regrets, just minor humiliation (I probably cut in half the value of the kids ugma account -- maybe that's why I take it so personal, lol). Eventually something will progress with the Ampa receptor--the potential is there. But in the end, it's still just another synthetic drug with a host of potential and unknown complications, and we all will die regardless, either as a result of it, or despite it. The rat race goes on...

Neuro said that AMPA upregulation (ionotropic variety) is no longer being pursued much by pharmas.

This may be true, but taking it a step further, why is this true? A great deal of this would be, logically, because of the failures of Stoll, Varney, and NP, for a plethora of reasons. Cortex was Ampakines, but now they've gone to pot :)

Getting back to being fucked up. A friend of mine (actually the brother of my best friend), has been frequenting concerts in the Philly area recently. He saw Tommy Cronwell (he sent me a link to a local interview with Tommy) and Trixie Whitley. Trixie, he said, is the daughter of a talented musician who he'd see play in NYC parks. Trixie's music is full of melancholy, but good. Her dad was a blues guitarist and had his own emotional/psychiatric issues growing up--I think he was bipolar or schizophrenic.

The moral is that good things can come out of fucked up things. That, for one, is why I'm expected great things from my boys! :)