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Re: mcbio post# 152780

Wednesday, 11/21/2012 5:54:38 AM

Wednesday, November 21, 2012 5:54:38 AM

Post# of 252254
I amuse I'm stating the obvious here but that pilot XOMA's trial was an open, uncontrolled, in 7 patients only, in Turkey (http://ard.bmj.com/content/71/4/563.abstract).
For the sake of comparison, this is AMGN's Kineret (a different anti IL-1 antibody, which is behind XOMA in Behçet’s disease) pilot trial - randomized, controlled, in 25 patients in US:

http://clinicaltrials.gov/ct2/show/NCT01441076?term=Beh%C3%A7et%E2%80%99s+uveitis&rank=9

Although data from that pilot study are good, I somehow get the feeling of rushing into phase III.

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