fwiw, here are the upcoming catalysts that are on my radar: 1) Ponatinib early approval-dec/jan (positive impact on revenue/cashflow) 2) Broad 2nd-line label(positive impact on revenue/competitive position) 3) Successful US ponatinib launch = upside surprise on sales/sales/sales 4) AP113 P1 read-out (ASCO?) 5) EMA approval and launch 6) AP113 registration trial (2nd-line ALK+ NSCLC) 7) EPIC Trial initial read-out 8) GIST or other pona registration trial Of these, #3 is the most important in terms of pps (fwiw, a new compound won't even move the needle)