Kraig Biocraft Laboratories Inc (KBLB)

[es1]

The best example of this I know of is right here...

In 1947, a housewife in the UK, Valerie Hunter Gordon, started developing and making Paddi, a 2-part system of a disposable pad (cellulose wadding covered with cotton wool) and an outer plastic, adjustable garment with press-studs/ snaps. Initially she used old parachutes for the garment. She applied for the patent in April 1948, and it was granted for the UK in October 1949. Initially the big manufacturers were unable to see the commercial possibilities of disposable nappies. In the UK in 1948, Valerie Hunter Gordon made over 400 Paddis herself using her sewing machine at the kitchen table. Her husband had unsuccessfully approached several companies for help until he had a chance meeting with Sir Robert Robinson at a business dinner. In November 1949 Valerie Gordon signed a contract with Robinsons of Chesterfield who then went into full production. In 1950 Boots the Chemist agreed to sell Paddi in all their UK branches. In 1951 the Paddi patent was granted for the USA and worldwide. Shortly after that, Playtex and several other large international companies tried unsuccessfully to buy out Paddi from Robinsons. Paddi was very successful for many years until the advent of 'all in one' diapers.[8]

The things to take from this IMO are
it took 2 years from concept to contract.
They failed many times to convince corperations that they had a product.
Many people were very wrong when they said it isnt a product.
They never gave up.