Avid Bioservices Inc (CDMO)

[freethemice]

Here is a picture of the structure of a capillary. Imagine these throughout a tumor and then bavituximab
binding to PS exposed in the lumen. The wall of the capillary has a layer of endothelial cells that is just one cell thick.
If macrophages bind to bavi and then eat holes in that layer of cells you can imagine the structure collapsing.