Aethlon Medical Inc (AEMD)

[ANESRI]

How cancer cells break free from tumors (These folks need to work with the HP)

http://web.mit.edu/newsoffice/2012/how-cancer-cells-break-free-from-tumors-1009.html




The researchers were surprised to find that adhesion tendencies of metastatic cells from different primary tumors were much more similar to each other than to those of the primary tumor from which they originally came. One pair of extracellular matrix molecules that metastatic tumors stuck to especially well was fibronectin and galectin-3, both made of proteins that contain or bind to sugars.



Preventing cancer spread

The findings offer potential new ways to block metastasis by focusing on a specific protein-protein or protein-sugar interaction, rather than a particular gene mutation, Reticker-Flynn says. “If those changes do confer a lot of metastatic potential, we can start thinking about how you target that interaction specifically,” he says.