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Re: zipjet post# 149912

Wednesday, 10/03/2012 9:51:03 AM

Wednesday, October 03, 2012 9:51:03 AM

Post# of 252816
SRPT:

I mumbled about this on twitter but I think the important observation about dystrophin production would be if the protein is actually incorporated into the costameres. Only then is it functionally meaningful.

The report that you get increased immunofluorescence is vague and doesn't necessarily demonstrate incorporation.
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